TABLE 2.

Co-mutation combinations and genomic locations identified in different proteins of SARS-CoV-2

Variation(s)	(Co)mutation(s)	No. of mutated proteins	No. of descendants
S→P	Nsp3	1	87
Y→C/P→L/S→P/L→S	Nsp13_1/Nsp13_2/Nsp3/ORF8	4	62
S→P/L→S	Nsp3-ORF8	1	22
P→L/D→G/Q→H/S→P/T→I	nsp12/S/ORF3a/Nsp3/Nsp2	5	30
P→L/Q→H/S→P/T→I	Nsp12/ORF3a/Nsp3/Nsp2	4	1
P→L/D→G/Q→H/S→P	Nsp12/S/ORF3a/Nsp3	4	3
L→F/S→P	Nsp6/Nsp3	2	16
L→F/S→P/L→S	Nsp6/Nsp3/ORF8	3	3
Y→C/P→L/L→F/S→P/L→S	Nsp13_1/Nsp13_2/Nsp6/Nsp3/ORF8	5	2
P→L/D→G/S→P	Nsp12/S/Nsp3	3	12