TABLE 3.
In silico docking analysis of SARS-CoV-2 proteins with human proteins
| SARS-CoV-2 | Host protein | Wild-type score | Mutant score | Differencea |
|---|---|---|---|---|
| S protein | ACE2 | 18296 | 17722 | 574 |
| S protein | TRMPSS2 | 20284 | 21180 | −896 |
| S protein | MYO5C | 18538 | 17390 | 1148 |
| Nsp13 | RPS6 | 17772 | 15750 | 2022 |
| Nsp13 | ATP6V1G1 | 14432 | 20242 | −5810 |
| Nsp12 | RPS6 | 16570 | 15750 | 820 |
| Nsp12 | ATP6V1G1 | 17150 | 20242 | −3092 |
| Nsp6 | RPS6 | 19336 | 17736 | 1600 |
| Nsp6 | ATP6V1G1 | 17614 | 16022 | 1592 |
| Nsp3 | RPS6 | 22888 | 21866 | 1022 |
| Nsp3 | ATP6V1G1 | 20760 | 21070 | −310 |
| Nsp2 | RPS6 | 22584 | 19540 | 3044 |
| Nsp2 | ATP6V1G1 | 18402 | 18592 | −190 |
a
Difference between the wild-type and mutant scores.