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. 2021 Oct 25;12:686876. doi: 10.3389/fphar.2021.686876

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Copyright © 2021 Zhang, Gu, Bian and Huang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Network diagrams of comparisons on all outcomes in this network meta-analysis. (A) Comparisons on dermatologic and endocrine irAEs in patients with advanced NSCLC. (B) Comparisons on pneumonitis in patients with advanced NSCLC. (C) Comparisons on colitis and hepatitis in patients with advanced NSCLC.(The circles represent treatment regimens and the size of each circle represents the number of participants, while the yellow line represents double-blind RCTs and the green is not blind.)