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Effects of miR-16-5p and ANLN on BC cell cycle and apoptosis. a-c Cell cycle and apoptosis was detected by flow cytometry after transfection of miR-16-5p mimcis, si-ANLN, NC or both in MCF-7 and MDA-MB 231 cells. Data represent the mean ± SD of three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001 compared with the NC group. NC, negative control
