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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Chem Biol Interact. 2021 Oct 8;350:109689. doi: 10.1016/j.cbi.2021.109689

Figure 8. Purified recombinant PTGR1 catalyzes the conversion of oxoFAs to their saturated products.

Figure 8.

(A) 15-ketoPGE2 (B) 11-oxoETE (C) 15-oxoETE (D) 17-oxoDHA (substrates only with no enzyme shown in black) were converted to their saturated metabolites in the presence of PTGR1 and NADH (white) but not in reaction buffer without enzyme. Similar results were obtained with NADPH instead of NADH (gray).