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. 2021 Nov 8;44:102191. doi: 10.1016/j.tmaid.2021.102191

Table 2.

Subgroup analyses performed in conjunctival hyperemia, conjunctival swab RT-PCR and risk of ocular manifestations.

Subgroup Conjunctival hyperemia
Conjunctival swab RT-PCR
Risk of ocular manifestations
N Proportion (95%CI) I2 Pa N Proportion (95%CI) I2 Pa N OR (95%CI) I2 Pa
Location 0.427 0.199 0.689
China 10 0.032 (0.011, 0.059) 82 7 0.010 (0.001, 0.033) 10 6 2.93 (1.48, 5.82) 0
Other Asian countries 7 0.151 (0.041, 0.306) 93 3 0.076 (0.018, 0.164) 65 3 2.28 (1.15, 4.53) 0
Europe 6 0.127 (0.044, 0.242) 92 4 0.059 (0.026, 0.101) 0 1 7.26 (0.36, 144.69) NA
United States 3 0.037 (0.002, 0.105) 95 0 NA NA 1 5.05 (0.84, 30.38) NA
Sample size 0.223 0.031 0.543
<100 13 0.092 (0.056, 0.135) 49 11 0.049 (0.024, 0.079) 20 4 2.30 (0.85, 6.20) 15
≥100 13 0.065 (0.031, 0.109) 96 3 0.023 (0.006, 0.049) 0 7 3.04 (1.75, 5.26) 0
Study design 0.811 0.709 0.490
Cross-sectional 11 0.077 (0.035, 0.132) 96 4 0.050 (0.008, 0.119) 77 4 3.22 (1.72, 6.04) 0
Case series 15 0.078 (0.034, 0.136) 89 10 0.034 (0.014, 0.061) 0 7 2.32 (1.17, 4.60) 0

Abbreviation: OR, odds ratio; 95% CI, 95 confidence intervals; N, study number; NA, not available.

a. P value for heterogeneity between subgroups with meta-regression analysis.