A) In vitro BBB transendothelial electrical resistance, B) Transport across BBB model, and C) pVGF transfection across BBB model. Data shown as mean (SD) with 4 repeats. ~, @, #, *, --, +, and “ shows statistically significant difference (p<0.05) from untreated, plain, Pen, MAN, CGN, RVG9R and RDP liposomes, respectively.