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. 2021 Oct 21;12:737708. doi: 10.3389/fimmu.2021.737708

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Copyright © 2021 Hakroush, Tampe, Ströbel, Korsten and Tampe

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Intrarenal subtypes of immune cell infiltrates in association with tubulointerstitial lesions in ANCA GN. (A) Distinct subtypes of immune cell infiltrates in association with tubulointerstitial lesions analogous to the Banff scoring system are shown by heatmap reflecting mean values of Spearman’s ρ, asterisks indicate p < 0.05. (B) Distinct subtypes of immune cell infiltrates in association with ATI lesions are shown by heatmap reflecting mean values of Spearman’s ρ, asterisks indicate p < 0.05. ah, arteriolar hyalinosis; ANCA, anti-neutrophil cytoplasmic antibodies; ATI, acute tubular injury; ci, interstitial fibrosis; ct, tubular atrophy; g, glomerulitis; GN, glomerulonephritis; i, interstitial inflammation; i-IFTA, inflammation in IFTA; RBC, red blood cell; t, tubulitis; ptc, peritubular capillaritis; ti, total inflammation; t-IFTA, tubulitis in IFTA; v, intimal arteritis.