Figure 7.

Intrarenal subtypes of immune cell infiltrates in MPO-ANCA versus PR3-ANCA GN. (A) Associations of clinical, laboratory parameters, and histopathological findings in MPO-ANCA GN are shown by heatmap reflecting mean values of Spearman’s ρ, asterisks indicate p < 0.05. (B) Associations of clinical, laboratory parameters and histopathological findings in PR3-ANCA GN are shown by heatmap reflecting mean values of Spearman’s ρ, asterisks indicate p < 0.05. ah, arteriolar hyalinosis; ANCA, anti-neutrophil cytoplasmic antibodies; ATI, acute tubular injury; BVAS, Birmingham Vasculitis Activity Score; ci, interstitial fibrosis; CRP, C-reactive protein; ct, tubular atrophy; eGFR, estimated glomerular filtration rate; g, glomerulitis; GN, glomerulonephritis; i, interstitial inflammation; IgG, immunoglobulin G; i-IFTA, inflammation in IFTA; MPA, microscopic polyangiitis; MPO, myeloperoxidase; RBC, red blood cell; RRT, renal replacement therapy; t, tubulitis; ptc, peritubular capillaritis; ti, total inflammation; t-IFTA, tubulitis in IFTA; uACR, urinary albumin-to-creatinine ratio; uPCR, urinary protein-to-creatinine ratio; v, intimal arteritis.