Table 4.

All-causality AEs occurring in >10% of all treated patients (N = 51)

AE	Grade 1		Grade 2		Grade 3		Grade 4
	n	%	n	%	n	%	n	%
Diarrhea	17	33	11	22	4	8	0	0
Nausea	20	39	7	14	0	0	0	0
Fatigue	4	8	9	18	0	0	0	0
Insomnia	11	22	2	4	0	0	0	0
Thrombocytopenia	4	8	3	6	4	8	2	4
Headache	9	18	3	6	0	0	0	0
Neutropenia	1	2	2	4	2	4	7	14
Dizziness	8	16	2	4	0	0	0	0
Peripheral edema	8	16	1	2	0	0	0	0
Cough	6	12	2	4	0	0	0	0
Rash	7	14	1	2	0	0	0	0
Rash, maculopapular	8	16	0	0	0	0	0	0
Anemia	1	2	4	8	2	4	0
Arthralgia	5	10	2	4	0	0	0	0
Contusion	7	14	0	0	0	0	0	0
Decreased appetite	5	10	2	4	0	0	0	0
Leukocytosis	0	0	0	0	7	14	0	0
Myalgia	5	10	2	4	0	0	0	0
Pneumonia	0	0	1	2	6	12	0	0
Pyrexia	4	8	2	4	1	2	0	0
Upper respiratory tract infection	4	8	3	6	0	0	0	0
Vomiting	5	10	2	4	0	0	0	0
AST/ALT increase	2	4	2	4	3	6	0	0

AST, aspartate aminotransferase.