Figure 2 .

The HCOP web tool interface. The ‘Input’ section shows the updated HCOP search form. The users select a primary species and one or more species that they wish to identify orthologs in. They then select the ortholog resources they wish to include in the search, and the type of search term, e.g. approved symbol, or database identifier, that they are providing. A single search term or list of search terms may be pasted into a text box or uploaded as a file to be used to run the search. The ‘Results’ section shows an example result panel. Information about the query gene appears in the dark blue section at the top of the panel, with each ortholog identified having its own section below this. Basic information about both the query and ortholog genes, as well as links to these genes in other resources, is displayed. Each ortholog section has an additional column labeled ‘Assertion derived from’ that contains a set of icons that represent the orthology sources that support this assignment.