TABLE 1.
Clinical characteristics of the 457 DIETFITS (Diet Intervention Examining the Factors Interacting with Treatment Success) study participants by examination phase1
| Examination 1 (baseline) | Examination 2 (6-mo follow-up) | P value | |
|---|---|---|---|
| Anthropometrics | |||
| Age, y | 39.8 ± 6.6 | — | — |
| Body weight, kg | 95.7 ± 14.8 | 88.4 ± 14.3 | <0.0001 |
| Body height, cm | 169.3 ± 9.5 | — | — |
| BMI, kg/m2 | 33.3 ± 3.6 | 30.8 ± 3.7 | <0.0001 |
| Systolic BP, mm Hg | 123.8 ± 12.5 | 119.3 ± 11.5 | <0.0001 |
| Diastolic BP, mm Hg | 81.3 ± 7.6 | 78.3 ± 7.3 | <0.0001 |
| Heart rate, bpm | 70.4 ± 10.1 | 67.5 ± 10.1 | <0.0001 |
| Biochemical data | |||
| HOMA-IR | 3.26 (1.71–7.26) | 2.26 (1.43–6.39) | <0.0001 |
| Total cholesterol, mg/dL | 189.2 ± 33.9 | 183.6 ± 35.1 | <0.0001 |
| LDL cholesterol, mg/dL | 114.2 ± 28.9 | 113.2 ± 29.7 | 0.32 |
| HDL cholesterol, mg/dL | 48.9 ± 9.8 | 49.2 ± 9.6 | 0.31 |
| Triglycerides, mg/dL | 113.1 (64.9–223.0) | 92.5 (54.5–180.5) | <0.0001 |
| sACE2, NPX | 1.89 ± 0.63 | 1.74 ± 0.54 | <0.0001 |
| Race/ethnicity | |||
| White | 328 (71.8) | — | |
| Black/African American | 14 (3.1) | — | |
| Asian | 48 (10.5) | — | |
| Other | 67 (14.7) | — | |
| DXA scan2 | |||
| BMC mass, kg | 2.59 ± 0.44 | 2.59 ± 0.44 | 0.45 |
| Fat mass, kg | 33.4 ± 7.5 | 28.8 ± 8.0 | <0.0001 |
| Lean mass, kg | 56.0 ± 11.3 | 54.1 ± 10.8 | <0.0001 |
| Fat percentage, % | 36.5 ± 6.8 | 33.7 ± 7.6 | <0.0001 |
1Values are arithmetic mean ± SD, geometric mean (10th–90th percentile), or participant n (%). P values reflect the significance of 6-mo longitudinal changes according to a paired-sample t test. BMC, bone mineral content; BP, blood pressure; NPX, Normalized Protein eXpression; sACE2, soluble angiotensin-converting enzyme 2.
2Baseline and follow-up data for DXA scan measurements were available in 352 participants.