TABLE 6.
Associations between conditional change in pregnancy urine CTX (Δ CTX) in the vitamin D–supplemented and placebo groups combined (total population), and neonatal DXA outcomes for the total body and total spine after adjustment for sex, infant age at DXA scan, and gestational age at birth1
| Total population | |||
|---|---|---|---|
| Δ CTX | n | β (95% CI) | P value |
| Neonatal total-body DXA | |||
| Total area, cm | 321 | 4.781 (1.567, 7.995) | 0.004 |
| Total BMC, g | 321 | 1.754 (0.798, 2.711) | <0.001 |
| Total BMD, g/cm2 | 321 | 0.003 (0.001, 0.005) | 0.002 |
| Neonatal total spine DXA | |||
| Total spine area, cm | 290 | 0.140 (0.027, 0.252) | 0.015 |
| Total spine BMC, g | 290 | 0.071 (0.022, 0.120) | 0.005 |
| Total spine BMD, g/cm2 | 290 | 0.004 (0.000, 0.008) | 0.038 |
1
Δ CTX = conditional change in CTX (late-pregnancy CTX adjusted for early-pregnancy CTX), SD. BMC, bone mineral content; BMD, bone mineral density; CTX, C-terminal telopeptide of type I collagen.