Table 3.
Patients clinical data. Clinical data of the 22 patients included in the study. The histopathological analysis showed that 11 patients are DCIS whereas six are DCIS adjacent to invasive disease (DCIS Adj. to IDC) and five have invasive features (IDC). We selected FFPE samples of different ages (1999–2017). ER: estrogen receptors, PR: progesterone receptors, HER2: human epidermal growth factor receptor 2 expression is qualitatively estimated (nonpresent (NP), 0–8) using histochemistry stains
| Patient ID | Age | Race | Date | Tumor type | Histopathological classification | ER | PR | HER2 | DCIS Size (mm) | DCIS nuclear grade | Invasive present |
|---|---|---|---|---|---|---|---|---|---|---|---|
| DCIS-017 | 66 | B | 2013 | Pure DCIS | Cribriform, solid | − | + | NA | 21 | 3 | No |
| DCIS-020-B3 | 67 | W | 2014 | Pure DCIS | Cribriform, solid, micrpapillary, comedo | + | + | NA | 40 | 2 | No |
| DCIS-020-B6 | 67 | W | 2014 | Pure DCIS | Cribriform, solid, micrpapillary, comedo | + | + | NA | 40 | 2 | No |
| DCIS-029-D5 | 34 | W | 2012 | Pure DCIS | Comedo | + | + | NA | 83 | 3 | No |
| DCIS-029-D8 | 34 | W | 2012 | Pure DCIS | Comedo | + | + | NA | 83 | 3 | No |
| DCIS-050 | 52 | W | 2010 | Synchronous DCIS | Cribriform, solid | + | + | − | 10 | 2 | Yes |
| DCIS-064 | 50 | OTHER | 2015 | Synchronous DCIS | Comedo | + | + | + | 75 | 3 | No |
| DCIS-080 | 49 | W | 2013 | Synchronous DCIS | Solid, comedo | + | + | − | 21 | 3 | Yes |
| DCIS-094-B11 | 68 | W | 2013 | IDC | Cribriform, solid, miropapillary | − | − | − | NA | 3 | Yes |
| DCIS-094-B7 | 68 | W | 2013 | IDC | Cribriform | − | − | − | NA | 3 | Yes |
| DCIS-122 | 47 | W | 2002 | Pure DCIS | Cribriform, solid, comedo | NA | NA | NA | 95 | 3 | No |
| DCIS-135 | 48 | B | 2013 | Pure DCIS | Cribiform, solid | + | + | NA | 13 | 2 | No |
| DCIS-163 | 53 | W | 2013 | Synchronous DCIS | Cribriform, solid, comedo | + | + | − | 54 | 3 | Yes |
| DCIS-164 | 65 | B | 2015 | IDC | Micropapilly, comedo | + | + | − | NA | 3 | Yes |
| DCIS-168-C4 | 63 | W | 2016 | IDC | Cribiform, solid | + | + | − | NA | 2 | Yes |
| DCIS-168-C8 | 63 | W | 2016 | IDC | Cribiform, solid | + | + | − | NA | 2 | Yes |
| DCIS-171 | 66 | B | 2000 | Synchronous DCIS | Solid | − | + | − | 15 | 3 | Yes |
| DCIS-178 | 56 | W | 2011 | Synchronous DCIS | Comedo, solid, micropapillary, papillary | − | − | − | NA | 3 | Yes |
| DCIS-211 | 43 | H | 2011 | Pure DCIS | Cribriform, solid, comedo | + | + | NA | 24 | 3 | No |
| DCIS-213 | 68 | W | 2009 | Pure DCIS | Cribriform, micrpapillary, comedo | + | + | NA | 16 | 3 | No |
| DCIS-222-B10 | 41 | A | 2013 | Pure DCIS | Cribiform, papillary | + | + | NA | 40 | 2 | No |
| DCIS-222-B6 | 41 | A | 2013 | Pure DCIS | Cribiform, papillary | + | + | NA | 40 | 2 | No |
| DCIS-225-A16 | 62 | B | 2011 | Pure DCIS | Cribiform, solid | + | + | NA | 30 | 2 | No |
| DCIS-225-A6 | 62 | B | 2011 | Pure DCIS | Cribiform, solid | + | + | NA | 30 | 3 | No |
| DCIS-227 | 75 | B | 2012 | Pure DCIS | Cribiform, solid, comedo | + | + | NA | 63 | 3 | No |
| DCIS-250 | 56 | W | 1999 | IDC | Cribiform, comedo | + | − | NA | NA | 3 | Yes |
| DCIS-267 | 66 | W | 2017 | IDC | Solid | + | + | − | 13 | 3 | Yes |
| DCIS-28-K12 | 42 | A | 2014 | Pure DCIS | Comedo, micropapillary | − | − | NA | 124 | 3 | No |