Table 2.
Prenatal | Postnatal | |||||
---|---|---|---|---|---|---|
No. of modules (BS) | No. of module genes | No. of avg −log10(P) | No. of modules (BS) | No. of module genes | No. of avg −log10(P) | |
AUD | 22 | 33 | 3.38 | 0 | 0 | − |
ALZ | 3 | 10a | 57.22 | 69 | 94 | 7.12 |
ALS | 10 | 18a | 2.27 | 35 | 54 | 2.17 |
ANEU | 1 | 4 | 6.55 | 0 | 0 | − |
Anxiety | 0 | 0 | − | 5 | 8 | 2.43 |
ADHD | 0 | 0 | − | 7 | 13 | 3.44 |
ASD | 1 | 3 | 2.67 | 0 | 0 | − |
BD | 22 | 33 | 3.88 | 2 | 5 | 4.92 |
DS | 5 | 13 | 4.17 | 22 | 43 | 4.28 |
EDU | 0 | 0 | − | 36 | 54 | 5.47 |
GNEU | 3 | 4 | 7.38 | 63 | 82 | 3.96 |
Height | 0 | 0 | − | 0 | 0 | − |
IP | 11 | 15 | 2.04 | 4 | 9 | 2.18 |
MDD | 0 | 0 | − | 0 | 0 | − |
MS | 4 | 12a | 5.71 | 83 | 102 | 3.70 |
NEU | 4 | 10 | 4.74 | 39 | 65 | 4.09 |
OCD | 28 | 48 | 1.99 | 0 | 0 | − |
PD | 0 | 0 | − | 29 | 48 | 1.95 |
SCZ | 44 | 77 | 6.97 | 16 | 24 | 7.79 |
COL | 2 | 4 | 4.25 | 20 | 38 | 3.02 |
SWB | 0 | 0 | − | 8 | 16 | 2.92 |
BS, BrainSpan.
−log10(P): average gene-based P-value from GWAS for module genes.
Bold cases indicate the conditions that were considered significant (see main text).
aCell growth and DNA replication-related pathway genes.