Table 2.
Databases providing annotation resources for circRNAs
| Database | Number of circRNAs | Short description | URL |
|---|---|---|---|
| circBase [63] | 92 375 | Provides information of circRNAs including the genomic position, gene symbols, evidence for the occurrence | http://www.circbase.org/ |
| CircNet [64] | 34 000 | Provides the information of circRNA expression profiles, circRNA-miRNA sponge regulatory network, circRNA-gene-miRNA regulatory network | http://circnet.mbc.nctu.edu.tw/ |
| deepBase v2.0 [65] | 14 867 | Provides comprehensive expression and evolution profiles of circRNAs. | http://biocenter.sysu. edu.cn/deepBase/ |
| circRNADb [66] | 32 914 | Provides the information of protein-coding potential of circRNAs | http://reprod.njmu.edu.cn/circrnadb |
| TSCD [67] | 302 853 | Provides the genomic location and conservation of tissue specific circRNAs | http://gb.whu.edu.cn/TSCD |
| CSCD [68] | 272 152 | Records the function and regulation of cancer-associated circRNAs | http://gb.whu.edu.cn/CSCD |
| CIRCpedia v2 [69] | 262 782 | Records the information of location, strand, isoform, expression value, sequencing type and conservation of circRNAs | https://www.picb.ac.cn/rnomics/circpedia/ |
| exoRBase [70] | 58 330 | Provides circRNA expression profile, expression rank, gene symbol and spliced length | http://www.exorbase.org/ |
| CircFunBase [71] | 7059 | Provides the information of circRNA function, GO annotations and circRNA-associated miRNAs | http://bis.zju.edu.cn/CircFunBase/ |
| TRCirc [72] | 92 375 | Contains more than 765 000 transcription factor-circRNA relationships | http://www.licpathway. net/TRCirc |
| circbank [73] | 140 790 | Develops a new naming system based on the host genes of circRNAs | http://www.circbank.cn/ |
| CircRiC [74] | 92 589 | Provides the modules of integrative analysis, drug response, biogenesis, and expression landscape | https://hanlab.uth.edu/cRic/ |
| MiOncoCirc [75] | 227 056 | Records circRNAs from metastases, primary tumors, and very rare cancer types | https://nguyenjoshvo.github.io/ |
| VirusCircBase [76] | 11 924 | Provides the information of the location, genes involved in the viral circRNA, the abundance, the detection method | http://www.computational biology.cn/ViruscircBase/home.html |