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. 2021 Aug 17;22(6):bbab315. doi: 10.1093/bib/bbab315

Table 10.

The top pathways for differentiating between LumB and the other three subtypes (Basal, LumA and Her2), using the Broad Institute’s curated pathway database

Pathway Genes in overlap Inline graphic -value
Genes down-regulated in basal subtype of breast cancer samples 27 1.15e-47
Genes up-regulated in bone relapse of breast cancer 39 4.25e-43
Genes down-regulated in ductal carcinoma versus normal ductal breast cells 24 2.6e-42
Genes down-regulated in nasopharyngeal carcinoma (NPC) positive for LMP1, a latent gene of Epstein–Barr virus (EBV) 29 1.85e-37
Genes up-regulated in breast cancer samples positive for ESR1 compared to the ESR1 negative tumours 26 1.82e-30