Table 1.
Summary of CRE definitions.
| Definition | ||||
|---|---|---|---|---|
| VA1 | VA2 | CDC1 | CDC2 | |
| Organisms |
Escherichia coli Klebsiella spp. Enterobacter spp. |
Escherichia coli K. pneumoniae/oxytoca Enterobacter spp. (especially E. cloacae) |
All Enterobacteriaceae |
All Enterobacteriaceae |
| Carbapenem criteria | Intermediate (“I”) or resistant (“R”) to imipenem, meropenem, and/or doripenem OR Resistant (“R”) to ertapenem AND (see next row) |
Resistant (“R”) to imipenem, meropenem, and/or doripenem | Intermediate (“I”) or resistant (“R”) to imipenem, meropenem, and/or doripenem AND (see next row) |
Resistant (“R”) to any carbapenem |
| Cephalosporin criteria | Resistant (“R”) to any tested 3rd-generation cephalosporin | None | Resistant (“R”) to all the following 3rd-gen cephalosporins that were tested: ceftriaxone, cefotaxime, ceftazidime | None |
| Additional criteria a | Positive Modified Hodge Test | Positive molecular diagnostic test (PCR) | Documented that organism produces a carbapenemase | |
a
These criteria were not assessed as part of this study
CRE, carbapenem-resistant Enterobacteriaceae; PCR, polymerase chain reaction