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. 2021 Nov 4;16:7433–7447. doi: 10.2147/IJN.S327737

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© 2021 Yan et al.

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In vitro and in vivo acoustic imaging of Cur-NBs. (A) Ultrasound images of Cur-NBs at different concentrations (0.0625 mg/mL, 0.125 mg/mL, 0.25 mg/mL, 0.5 mg/mL) in B-mode and nonlinear contrast mode in vitro. (B) Quantification of the acoustic signals in B-mode (n = 3). (C) Quantification of the acoustic signals in nonlinear contrast mode (n = 3). (D) The acoustic signals of intracranial contrast imaging of injected Cur-NBs of PBS (the white dotted line is the removed skull). (E) The time curve of acoustic signals with injected Cur-NBs or PBS.