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. Author manuscript; available in PMC: 2022 May 24.
Published in final edited form as: Curr Biol. 2021 May 24;31(10):R560–R573. doi: 10.1016/j.cub.2021.02.035

Table 1.

Model parameters of prominent biochemical and chemomechanical models of microtubule growth. Dwell times are calculated by using free energy to solve for the equilibrium constant, using the on-rate to calculate the off-rate, and inverting the off-rate.

Paper kon (μM−1 s−1 pf−1) ΔGlong (kBT) ΔGlat (kBT) Loner dwell time (ms) Corner dwell time (ms)
Mickolajcyzk et al. 201945 0.8 - Yeast −12 −3.6 203.4 7445.7
Schaedel et al. 201946 1 −18.8 −9.4 0.1a 984.6a
Margolin et al. 2012118 1.25 −9.4 −0.3 9.7 13.1
Thawani et al.60 1.3 −7.2 −6.5 1 685.3
vanBuren et al. 200222 2 −9.4 −3.2 6 148.3
4 −6.8 −5.7 0.2 67.1
Piedra et al. 201526 4 - Yeast −5.8 −6.6 0.1 60.7
Gardner et al. 2011 64 4 −9.5 −5 3.3 495.7
Coombes et al. 201352 5 −7.2 −5.7 0.3 80.1
Chaaban et al. 201841 6 – C. elegans −7.1 −6.4 0.2 121.6
6 −6.3 −5 0.1 13.5
Zakharov et al. 2015116 0.63 −15.5 −9.1
McIntosh et al. 201875 0.63 −16.6 −5.3
Gudimchuk et al. 2020117 0.63 −16.9 −13.5
Castle et al. 201363 12.7 - Loner −6.7 0.1 a
7.4 - Corner −6.7 −3.6 4 a

Notes:

a

Includes entropic penalty specified in the paper.