Table 4.

Adverse reactions

	All 4 doses of TXA	1–3 Doses of TXA	No TXA	Overall	P value
Number	70	50	89	209	∗	†	‡
Minor adverse events	11 (16%)	6 (12%)	9 (10%)	26 (12%)	.921	.856	.556
Major adverse event	1 (1.43%)	0 (0%)	1 (1.12%)	2 (0.96%)	.711	.793	.979

This table shows the number patients who reported symptoms that could possibly include an adverse reaction of TXA. There were no differences in both major and minor adverse reactions between the 2 cohorts of patients. Minor adverse events included headache, sinus congestion, hives, nausea, abdominal pain, diarrhea, a new musculoskeletal complaint, or a seizure. Major adverse events included pulmonary embolus, heart attack, or stroke.

^∗Denotes the P value derived from a comparison between the group who received all 4 doses of TXA and the group who received between 1 and 3 doses of TXA.

^†Denotes the P value derived from a comparison between the group who received between 1 and 3 doses of TXA and the group who received no TXA.

^‡Denotes the P value derived from a comparison between the group who received all 4 doses of TXA and the group who received no TXA.