Table 8.
Outcomes of hip fracture patients by TXA cohort
| Characteristics | All 4 doses of TXA | 1–3 Doses of TXA | No TXA | P value | ||
|---|---|---|---|---|---|---|
|
|
||||||
| Total N | 70 | 50 | 89 | ∗ | † | ‡ |
| Baseline Labs | ||||||
| Admission Hemoglobin (SD) | 12.5 (1.61) | 12.0 (1.67) | 11.5 (1.66) | .217 | .184 | <.001 |
| Admission Hematocrit % (SD) | 38.3 (4.55) | 36.9 (4.75) | 35.6 (5.02) | .281 | .233 | .001 |
| Outcomes | ||||||
| Transfusion % | 7.1% | 22.0% | 28.1% | .101 | .650 | .003 |
| Estimated Blood Loss (SD) | 137 (82) | 138 (125) | 168 (121) | 1.000 | .276 | .201 |
| POD1 Hemoglobin (SD) | 10.2 (1.90) | 9.9 (1.95) | 9.2 (1.58) | .460 | .073 | .001 |
| Change in POD1 Hemoglobin (SD) | 2.29 (1.22) | 2.37 (2.00) | 2.39 (1.38) | .866 | .619 | .896 |
| POD2 Hemoglobin (SD) | 9.8 (1.71) | 9.4 (1.88) | 8.6 (1.38) | .405 | .017 | <.001 |
| Change POD2 Hemoglobin (SD) | 2.76 (1.39) | 2.54 (1.53) | 2.95 (1.42) | .714 | .255 | .666 |
This table demonstrates outcome characteristics of hip fracture patients by TXA cohort. The 4 dose TXA cohort had a higher average admission hemoglobin and hematocrit, higher postoperative day 1 and day 2 hemoglobin values, and a shorter hospital length of stay, compared to the cohort that did not receive TXA. There were no differences between the 1 and 3 dose TXA cohort and the other cohorts.
POD = postoperative day.
Denotes the P value derived from a comparison between the group who received all 4 doses of TXA and the group who received between 1 and 3 doses of TXA.
Denotes the P value derived from a comparison between the group who received between 1 and 3 doses of TXA and the group who received no TXA.
Denotes the P value derived from a comparison between the group who received all 4 doses of TXA and the group who received no TXA.