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. 2021 Sep 15;4(4):e147. doi: 10.1097/OI9.0000000000000147

Table 8.

Outcomes of hip fracture patients by TXA cohort

Characteristics All 4 doses of TXA 1–3 Doses of TXA No TXA P value

Total N 70 50 89
Baseline Labs
 Admission Hemoglobin (SD) 12.5 (1.61) 12.0 (1.67) 11.5 (1.66) .217 .184 <.001
 Admission Hematocrit % (SD) 38.3 (4.55) 36.9 (4.75) 35.6 (5.02) .281 .233 .001
Outcomes
 Transfusion % 7.1% 22.0% 28.1% .101 .650 .003
 Estimated Blood Loss (SD) 137 (82) 138 (125) 168 (121) 1.000 .276 .201
 POD1 Hemoglobin (SD) 10.2 (1.90) 9.9 (1.95) 9.2 (1.58) .460 .073 .001
 Change in POD1 Hemoglobin (SD) 2.29 (1.22) 2.37 (2.00) 2.39 (1.38) .866 .619 .896
 POD2 Hemoglobin (SD) 9.8 (1.71) 9.4 (1.88) 8.6 (1.38) .405 .017 <.001
 Change POD2 Hemoglobin (SD) 2.76 (1.39) 2.54 (1.53) 2.95 (1.42) .714 .255 .666

This table demonstrates outcome characteristics of hip fracture patients by TXA cohort. The 4 dose TXA cohort had a higher average admission hemoglobin and hematocrit, higher postoperative day 1 and day 2 hemoglobin values, and a shorter hospital length of stay, compared to the cohort that did not receive TXA. There were no differences between the 1 and 3 dose TXA cohort and the other cohorts.

POD = postoperative day.

Denotes the P value derived from a comparison between the group who received all 4 doses of TXA and the group who received between 1 and 3 doses of TXA.

Denotes the P value derived from a comparison between the group who received between 1 and 3 doses of TXA and the group who received no TXA.

Denotes the P value derived from a comparison between the group who received all 4 doses of TXA and the group who received no TXA.