Table 1.
Comparison of patient characteristics at baseline.
| Term | BFHX (N = 64) | Placebo (N = 65) | P-value a |
|---|---|---|---|
| Male (%) | 31 (48.44) | 29 (44.62) | 0.7254 |
| Age (years, ) | 54.16 ± 12.11 | 52.51 ± 12.31 | 0.4448 |
| Age group (years, %) | 0.7810 | ||
| 18–40 | 6 (9.38) | 8 (12.31) | |
| 41–64 | 47 (73.44) | 44 (67.69) | |
| 65–75 | 8 (12.50) | 11 (16.92) | |
| >75 | 3 (4.69) | 2 (3.08) | |
| Height (cm) | 164.80 ± 7.21 | 163.94 ± 7.65 | 0.5163 |
| Weight (kg) | 68.08 ± 11.78 | 65.92 ± 9.80 | 0.2603 |
| BMI (kg/m2) | 24.995 ± 3.536 | 24.474 ± 2.894 | 0.3607 |
| Han nationality (%) | 64 (100.00) | 65 (100.00) | – |
| Manual labour (%) | 12 (18.75) | 9 (13.85) | 0.4835 |
| Marriage | 0.3800 | ||
| Married | 58 (90.63) | 62 (95.38) | |
| Unmarried | 5 (7.81) | 3 (4.62) | |
| Other | 1 (1.56) | 0 (0.00) | |
| Severe/critical patients (%) | 13 (20.31) | 7 (10.77) | 0.1516 |
| Time from confirmation to randomisation (day) | 131.2 ± 14.0 | 130.7 ± 14.6 | 0.8254 |
| Time from discharge to randomisation (day) | 94.3 ± 17.0 | 94.3 ± 20.5 | 0.9845 |
| Comorbidities (N, %) | |||
| Rheumatic diseases | 1 (1.56) | 0 (0.00) | 0.4961 |
| Respiratory diseases | 2 (3.13) | 1 (1.54) | 0.6191 |
| Urinary system diseases | 1 (1.56) | 1 (1.54) | 1.0000 |
| Endocrine and metabolic system diseases | 11 (17.19) | 10 (15.38) | 0.8155 |
| Nervous system diseases | 1 (1.56) | 0 (0.00) | 0.4961 |
| Digestive system diseases | 1 (1.56) | 6 (9.23) | 0.1148 |
| Cardiovascular diseases | 12 (18.75) | 13 (20.00) | 1.0000 |
| Ophthalmic Diseases | 1 (1.56) | 0 (0.00) | 0.4961 |
| Classification of concomitant medication (N, %) | |||
| Digestive and metabolic system | 10 (15.63) | 5 (7.69) | 0.1807 |
| Cardiovascular system | 9 (14.06) | 10 (15.38) | 1.0000 |
| Chinese medicine/Chinese patent medicine | 3 (4.69) | 1 (1.54) | 0.3652 |
| Blood system | 2 (3.13) | 5 (7.69) | 0.4401 |
| Endocrine system | 1 (1.56) | 1 (1.54) | 1.0000 |
| Respiratory system | 1 (1.56) | 0 (0.00) | 0.4961 |
| Motor system | 1 (1.56) | 0 (0.00) | 0.4961 |
| Nervous system | 1 (1.56) | 0 (0.00) | 0.4961 |
| Antibiotics | 1 (1.56) | 0 (0.00) | 0.4961 |
| Combined | 1 (1.56) | 0 (0.00) | 0.4961 |
a
P-values were calculated for continuous outcomes with t-tests for the change from baseline to the last visit after three months of treatment; Fisher’ s exact test was performed for categorical outcomes.