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. 2021 Oct;10(10):3946–3952. doi: 10.21037/tau-20-1084

Figure 1.

Figure 1

Comparison of KDM5D expression in tumor cells (A) and benign cells (B) in radical prostatectomy specimens of docetaxel responders and non-responders. (C) Absolute number of Ki-67 index (% of positive cells in correlation to total cell number of evaluated area) in docetaxel responders and non-responders. Data presented as mean ± SEM, statistics: unpaired t-test, *, P<0.05; **, P<0.01; ***, P<0.001 (n=21); (D,E) Representative pictures of corresponding stainings (AMACR/p63 IHC-cancer: AMACR positive/p63 negative; benign: AMACR negative/p63 positive, KDM5D ISH and Ki-67 IHC) of a non-responder (D) with low KDM5D expression in cancer and benign and low Ki-67 in cancer and a responding patient (E) with high KDM5D expression in cancer and benign and high Ki-67 in cancer. Magnification ×40 (scale bar 20 µm). IHC, immunohistochemistry; ISH, in situ hybridization.