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. 2021 Oct;10(10):3918–3930. doi: 10.21037/tau-20-1118

Table 3. High volume/risk criteria for metastatic prostate cancer.

CHAARTED high volume criteria LATITUDE high risk criteria
>4 bone metastases (at least one outside the spine or pelvis AND/OR Visceral metastases Two or more of the following criteria:
• >3 bone metastases
• Gleason score >8
• Visceral metastases (not including lymph node metastases)