Table 2.

Premenstrual symptoms scores in placebo and garlic groups before (cycle 0) and after intervention (cycles 1, 2, and 3).

Symptoms		Groups		Mean difference between groups (95% CI)	P−value
		Placebo (n = 64) mean ± SD	Garlic (n = 65) mean ± SD
Mood symptoms	Cycle 0 Cycle 1 Cycle 2 Cycle 3	7.43 ± 2.18 6.28 ± 2.21 5.76 ± 2.02 5.18 ± 1.85	7.56 ± 2.09 4.95 ± 1.92 3.67 ± 2.03 2.33 ± 1.92	−0.13 (−0.08–0.61) 1.32 (0.60–2.04) 2.08 (1.37–2.79) 2.84 (2.18–3.50)	0.727 <0.001 <0.001 <0.001
Behavioral symptoms	Cycle 0 Cycle 1 Cycle 2 Cycle 3	13.29 ± 4.38 11.73 ± 3.82 10.50 ± 3.48 9.57 ± 3.27	13.46 ± 3.87 9.53 ± 4.16 7.24 ± 4.04 5.07 ± 3.58	−0.16 (−1.60–1.27) 2.19 (0.80–3.58) 3.25 (1.93–4.57) 4.50 (3.30–5.69)	0.822 0.002 <0.001 <0.001
Physical symptoms	Cycle 0 Cycle 1 Cycle 2 Cycle 3	5.64 ± 2.52 5.10 ± 2.74 4.54 ± 2.63 4.06 ± 2.43	5.50 ± 3.01 3.81 ± 2.24 2.72 ± 2.24 1.93 ± 1.86	0.13 (−0.83–1.10) 1.29 (0.43–2.16) 1.82 (0.97–2.67) 2.12 (1.36–2.88)	0.787 0.004 <0.001 <0.001
Interfering symptoms	Cycle 0 Cycle 1 Cycle 2 Cycle 3	6.98 ± 2.34 6.26 ± 2.53 5.87 ± 2.32 5.43 ± 2.18	7.55 ± 2.03 5.03 ± 2.41 3.18 ± 2.05 1.86 ± 1.77	−0.56 (−1.33–0.19) 1.23 (0.37–2.09) 2.69 (1.92–3.45) 3.57 (2.88–4.26)	0.143 0.005 <0.001 <0.001
Total symptoms	Cycle 0 Cycle 1 Cycle 2 Cycle 3	33.35 ± 7.96 29.39 ± 8.33 26.68 ± 7.58 24.28 ± 7.22	34.09 ± 7.31 23.33 ± 7.67 16.83 ± 7.78 11.21 ± 7.17	−0.74 (−3.99–1.93) 6.05 (3.26–8.84) 9.85 (7.17–12.53) 13.07 (10.55–15.57)	0.587 <0.001 <0.001 <0.001

Resulted from repeated measures ANOVA test based on comparing the mean difference between two groups.