Table 1. Genetic test items that were approved for DTC-GT in 2016 (12 test items and 46 genes).
| # | Test items (number of genes) | Genes |
|---|---|---|
| 1 | BMI (3) | FTO, MC4R, BDNF |
| 2 | Triglycerides concentration (8) | GCKR, DOCK7, ANGPTL3, BAZ1B, TBL2, MLXIPL, LOC105375745, TRIB1 |
| 3 | Cholesterol (8) | CELSR2, SORT1, HMGCR, ABO, ABCA1, MYL2, LIPG, CETP |
| 4 | Blood sugar (8) | CDKN2A/B, G6PC2, GCK, GCKR, GLIS3, MTNR1B, DGKB-TMEM195, SLC30A8 |
| 5 | Blood pressure (8) | NPR3, ATP2B1, NT5C2, CSK, HECTD4, GUCY1A3, CYP17A1, FGF5 |
| 6 | Pigmentation (2) | OCA2, MC1R |
| 7 | Hair loss (3) | chr20p11 (rs1160312, rs2180439), IL2RA, HLA-DQB1 |
| 8 | Hair thickness (1) | EDAR |
| 9 | Skin aging (1) | AGER |
| 10 | Skin elasticity (1) | MMP1 |
| 11 | Vitamin C concentration (1) | SLC23A1 (SVCT1) |
| 12 | Caffeine metabolism (2) | AHR, CYP1A1, CYP1A2 |
DTC-GT, direct-to-consumer genetic testing; BMI, body mass index.