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. 2021 Oct 25;11:755113. doi: 10.3389/fonc.2021.755113

Table 1.

Demographics and clinical characteristics of patients.

Variable N (%)
Total 2,293
Gender
Male 958 (41.8)
Female 1,335 (58.2)
Age
Median 69 (21–90)
STD 14.78
Race
White 2,004 (87.4)
African American 188 (8.2)
Others 101 (4.4)
Year of diagnosis
2010 413 (18.0)
2011 566 (24.7)
2012 633 (27.6)
2013 681 (29.7)
Charlson–Deyo score
0 1,540 (67.2)
1 537 (23.4)
2+ 216 (9.4)
Site
Appendix 8 (0.4)
Cecum 621 (27.1)
Ascending colon 746 (32.5)
Hepatic flexure 143 (6.2)
Transverse colon 301 (13.1)
Splenic flexure 80 (3.5)
Descending colon 115 (5.0)
Sigmoid colon 222 (9.7)
Overlapping 36 (1.6)
Not otherwise specified 21 (0.9)
Surgery at primary site
Partial colectomy 487 (21.2)
Subtotal colectomy/hemicolectomy 1,722 (75.1)
Total colectomy 42 (1.8)
Total proctocolectomy 10 (0.4)
Unknown 32 (1.4)
Grade
Well differentiated/moderately differentiated 1,540 (67.2)
Poorly differentiated/undifferentiated 753 (32.8)
Pathological T stage
T3 1,957 (85.3)
T4 321 (14.0)
Risk group per study
High risk 676 (29.5)
Not high risk 1,617 (70.5)
High-risk features a
T4 321 (14.0)
LVI 329 (14.3)
<12 lymph node removed 89 (3.9)
Positive margin 69 (3.0)
Systemic/surgery sequence
No systemic therapy 1,862 (81.2)
Systemic therapy after surgery 431 (18.8)
Chemotherapy
No chemotherapy 1,862 (81.2)
Single-agent chemotherapy 108 (4.7)
Multiagent chemotherapy 292 (12.7)
Chemotherapy type and number of agents not documented 31 (1.4)
a

High-risk features not mutually exclusive.