Table 3.
Subgroup analyses.
| Incidence of CTEPH in acute PE patients | ||||
|---|---|---|---|---|
| Study characteristics | Datasets number | Incidence (95% CI) | I2 (%) | P for subgroup difference |
| Ethnicity | ||||
| Europids | 16 | 1.96 (1.29, 2.63) | 78 | |
| Asians | 6 | 5.08 (2.67, 7.49) | 81 | 0.01 |
| Study design | ||||
| PC | 18 | 2.47 (1.76, 3.18) | 83 | |
| RC | 4 | 4.75 (3.04, 6.46) | 0 | 0.02 |
| Patient characteristics | ||||
| Consecutive acute PE patients | 2 | 0.64 (0.00, 1.30) | 29 | |
| Acute PE survivors | 10 | 4.36 (2.72, 5.99) | 82 | |
| Acute PE survivors without major comorbidity | 10 | 2.60 (1.56, 3.65) | 83 | <0.001 |
| Sample size | ||||
| >230 | 11 | 1.71 (1.04, 2.39) | 84 | |
| ≤ 230 | 11 | 4.57 (3.53, 5.60) | 0 | <0.001 |
| Patient selection for CTEPH | ||||
| All patients | 8 | 3.56 (1.82, 5.29) | 80 | |
| Selected patients | 14 | 2.85 (1.97, 3.74) | 85 | 0.48 |
| Primary test for CTEPH | ||||
| TTE | 20 | 2.65 (1.93, 3.36) | 83 | |
| V/Q lung scan | 2 | 4.76 (2.48, 7.05) | 0 | 0.08 |
PE, pulmonary embolism; CTEPH, chronic thromboembolic pulmonary hypertension; RC, retrospective cohort; PC, prospective cohort; TTE, Transthoracic echocardiography; V/Q, ventilation-perfusion; CI, confidence interval.