Table 2.

Overview of experimental animal groups.

Rat line	Sample size	Treatment
FSL	n = 10	FMT from patients with MDD (FMT-MDD)
	n = 10	FMT from healthy individuals (FMT-Healthy)
	n = 10	Control with autotransplantation of own faeces (CON-Auto)
	n = 10	Control with oral gavage of demineralised water (CON-H2O)
FRL	n = 10	FMT from patients with MDD (FMT-MDD)
	n = 10	FMT from healthy individuals (FMT-Healthy)
	n = 10	FMT from patients with MDD combined with sertraline (FMT-MDD-Ser)
	n = 10	Control with autotransplantation of own faeces (CON-Auto)
	n = 10	Control with oral gavage of demineralised water (CON-H2O)

FSL (n = 40) and FRL (n = 50) rats were used. Animal groups (n = 10 per group) received either faecal microbiota transplantations (FMT) from patients with MDD (FMT-MDD), FMT from healthy individuals (FMT-Healthy), FMT with their own faeces (CON-Auto) or water by oral gavage (CON-H2O). Additionally, one group of FRL rats received FMT from patients with MDD combined with simultaneous treatment with sertraline (FMT-MDD-Ser).