Skip to main content
. 2021 Jul 14;125(10):1321–1332. doi: 10.1038/s41416-021-01469-9

Table 1.

Prevalence of germline BRCA1/2 mutations in apparently sporadic pancreatic cancer.

Authors/year Total no. of PDAC patients BRCA1/2 mutations no. patients (%) Reference
Holter et al., 2015 306

BRCA1: 3 (0.98%)

BRCA2: 11 (3.59%)

[11]
Shindo et al., 2017 854

BRCA1: 3 (0.35%)

BRCA2: 12 (1.4%)

[55]
Grant et al., 2015 290

BRCA1: 1 (0.34%)

BRCA2: 2 (0.68%)

[63]
Hu et al., 2018 2999

BRCA1: 18 (0.6%)

BRCA2: 57 (1.9%)

[64]
Brand et al., 2018 298

BRCA1: 4 (1.34%)

BRCA2: 4 (1.34%)

[65]
Yurgelun et al., 2019 289

BRCA1: 3 (1.03%)

BRCA2: 4 (1.38%)

[66]

PDAC pancreatic ductal adenocarcinoma.