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. 2021 Nov 8;11:21601. doi: 10.1038/s41598-021-00844-z

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© The Author(s) 2021, corrected publication 2021

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Average normalized antibody binding stratified by age group for human anti-IgGs targeting the native (black), B.1.351 (red), B.1.617.2 (blue) and P.1 (gray) spike proteins among variant-naïve, non-hospitalized individuals. SPR and ELISA data from weeks 4 and 16 post-diagnosis were normalized to the mean of the overall cohort and pooled. A normalized antibody binding of 1 thus refers to a response equivalent to the average of all SARS-CoV-2-positive individuals (n = 8 for each data set) and the error bars correspond to one standard deviation). Ctrls: SARS-CoV-2-negative sera (n = 8).