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. 2021 Aug 18;125(10):1443–1449. doi: 10.1038/s41416-021-01496-6

Table 1.

Patient characteristics.

Initial DCIS treatment
BCS only, N = 2647 BCS + RT, N = 2604 Mastectomy, N = 4794 Total, N = 10,045
Follow-up (years), median (IQR) 17.0 (9.7–24.4) 14.5 (9.9–19.1) 16.0 (9.0–22.9) 15.7 (9.2–22.3)
Age at DCIS diagnosis (years), median (IQR) 58.9 (43.0–74.8) 57.2 (43.2–71.2) 57.2 (40.6–73.8) 57.6 (41.9–73.3)
 Age <50 474 (17.9) 457 (17.5) 1212 (25.3) 2143 (21.3)
 Age ≥50 2173 (82.1) 2147 (82.5) 3582 (74.7) 7902 (78.7)
DCIS grade (1999–2004a)
 Low (1) 302 (40.9%) 215 (13.7%) 190 (10.2%) 707 (16.9%)
 Intermediate (2) 234 (31.7%) 578 (36.7%) 553 (29.7%) 1365 (32.7%)
 High (3) 202 (27.4%) 780 (49.6%) 1121 (60.1%) 2103 (50.4%)
 Unknown 240 285 342 867
Subsequent iIBC 445 240 89 774
Subsequent iDCIS 352 145 NA 497

iIBC ipsilateral invasive breast cancer, iDCIS ipsilateral ductal carcinoma in situ, BCS breast-conserving surgery, RT radiotherapy, N number, IQR interquartile range, DCIS ductal carcinoma in situ, NA not available.

aData on grade are presented for patients diagnosed with primary DCIS from 1999 to 2004 (n = 5042).