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. 2021 Nov 8;11:21886. doi: 10.1038/s41598-021-01380-6

Table 2.

Mixed-effects linear regression analysis of the association between race and mean macular capillary parameters.

Macular capillary parameter Regression coefficient P value Regression coefficient* P* value
SCP VD (%)
Fovea 2.53 (0.37–5.04) 0.047 2.81 (0.084–5.54) 0.043
Parafovea 1.71 (0.45–2.97) 0.008 1.37 (0.27–2.47) 0.014
Total area of fovea and parafovea 0.98 (− 0.31–2.26) 0.136 0.66 (− 0.54–1.86) 0.284
ICP VD (%)
Fovea 4.21 (1.24–7.18) 0.005 3.96 (0.82–7.11) 0.014
Parafovea 2.24 (0.69–3.78) 0.005 2.64 (0.98–4.30) 0.002
Total area of fovea and parafovea 1.26 (− 0.23–2.76) 0.097 1.54 (0.01–3.06) 0.048
DCP VD (%)
Fovea 1.67 (− 0.91–4.26) 0.205 2.28 (− 0.41–4.96) 0.096
Parafovea 1.25 (− 1.28–3.78) 0.332 2.25 (− 0.42–4.92) 0.098
Total area of fovea and parafovea 0.86 (− 1.48–3.19) 0.473 1.54 (− 0.98–4.07) 0.23
FAZ Area (mm2)  − 0.10 (− 0.16–(− 0.05))  < 0.001  − 0.07 (− 0.12–(− 0.02) 0.006
FAZ Perimeter (mm)  − 0.29 (− 0.46–(− 0.12)) 0.001  − 0.23 (− 0.41–(− 0.47)) 0.014
FAZ Acircularity Index 0.035 (0.008–0.061) 0.01 0.023 (− 0.002–0.49) 0.076
FD-300  − 2.64 (− 4.02–(− 1.23))  < 0.001  − 2.34 (− 3.71–(− 0.97)) 0.001
Choriocapillaris BFA (%)
Fovea 1.2 (0.06–2.3) 0.039 1.1 (− 0.10–2.3) 0.073
Parafovea 2.4 (0.46–4.4) 0.016 2.4 (0.19–4.6) 0.033
Total area of fovea and parafovea 1.5 (0.47–2.5) 0.004 1.5 (0.34–2.6) 0.011

Regression Coefficient and P value accounting for 2 eyes of the same subject. Regression Coefficient* and P* value accounting for 2 eyes of the same subject and adjusting for axial length. VD = vessel density. SCP = superficial capillary plexus. ICP = intermediate capillary plexus. DCP = deep capillary plexus. FAZ = foveal avascular zone. FD-300 = capillary density in a 300 μm wide region around the FAZ. BFA = blood flow area.