Table 2.
Wilcoxon test comparing different layers in proprietary and cross-platform softwares.
| Qualitative comparison of grading of retinal segmentation using cross-platform (Orion) and proprietary (Heidelberg) softwares to visual verification, in normal, intermediate dry AMD and diabetic macular edema eyes | |||
|---|---|---|---|
| Mean ± SD [Proprietary software (Heidelberg)] | Mean ± SD [Cross platform software (Orion)] | p-value | |
| Normal eyes (N = 45) | |||
| NFL | 1.42 ± 0.50 | 1.09 ± 0.36 | 0.001 |
| GCIPL | 1.16 ± 0.37 | 1.02 ± 0.15 | 0.07 |
| INL | 1.22 ± 0.47 | 1.00 ± 0.00 | 0.004 |
| OPL | 1.11 ± 0.38 | 1.00 ± 0.00 | 0.13 |
| ONL | 1.04 ± 0.21 | 1.04 ± 0.21 | 1.00 |
| NFL | 1.39 ± 0.56 | 1.15 ± 0.44 | 0.04 |
| Intermediate dry AMD eyes (N = 33) | |||
| GCIPL | 1.21 ± 0.55 | 1.18 ± 0.53 | 0.88 |
| INL | 1.30 ± 0.53 | 1.15 ± 0.44 | 0.18 |
| OPL | 1.33 ± 0.60 | 1.21 ± 0.49 | 0.41 |
| ONL | 1.46 ± 0.62 | 1.58 ± 0.66 | 0.49 |
| NFL | 2.00 ± 1.08 | 1.63 ± 0.81 | 0.11 |
| Diabetic Macular Edema eyes (N = 30) | |||
| GCIPL | 1.83 ± 1.09 | 1.43 ± 0.68 | 0.05 |
| INL | 2.43 ± 0.97 | 1.27 ± 0.64 | 0.00 |
| OPL | 2.20 ± 1.19 | 1.53 ± 0.68 | 0.003 |
| ONL | 1.83 ± 1.02 | 1.70 ± 0.70 | 0.49 |
Segmentation quality grading scheme: 1 = Good, 2 = Mild, 3 = Moderate, 4 = Severe.