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Mechanisms involved in bispecific antibody mediated cytotoxicity. A: Non-MHC restricted perforin/granzyme B mediated killing by redirected T cells. B: Antibody dependent cellular cytotoxicity mediated by Fc-recepter binding of bipecific antibody, NK cell and effector T cell. C: Antibody dependent cellular cytotoxicity mediated by T effector cell and monocyte.
