TABLE 1.
Cancer antigen | Example of BsAb | Ref |
---|---|---|
Trop2 | CD3 x Trop2 | 57 |
EGFR | CD3 x EGFR EGFR x mPEG |
58
59 |
EphA10 | CD3 x EphA10 | 60 |
P-cadherin | CD3 x cadherin | 61 |
EpCAM | CD3 x EpCAM | 6,30 |
CEACAM5 | CD3 x CEACAM5 | 57 |
HER2 | mPEG x HER2 | 62 |
HER3 | HER3 x EGFR HER2 x HER3 |
45
63 |
p95HER2 | CD3 x p95HER2 | 48 |
Notch | EGFR x Notch | 46 |
MAGE-A4 | MAGE-A4 x CD3 | 64 |
Mesothelin | CD16 x mesothelin | 47 |
Muc1 | CD16 x MUC1 | 65 |