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. Author manuscript; available in PMC: 2023 Aug 1.
Published in final edited form as: Expert Opin Biol Ther. 2021 May 9;22(8):1017–1027. doi: 10.1080/14712598.2021.1922665

TABLE 1.

Cancer antigens relevant to breast cancer and examples of BsAbs reported to target those antigens.

Cancer antigen Example of BsAb Ref
Trop2 CD3 x Trop2 57
EGFR CD3 x EGFR
EGFR x mPEG
58
59
EphA10 CD3 x EphA10 60
P-cadherin CD3 x cadherin 61
EpCAM CD3 x EpCAM 6,30
CEACAM5 CD3 x CEACAM5 57
HER2 mPEG x HER2 62
HER3 HER3 x EGFR
HER2 x HER3
45
63
p95HER2 CD3 x p95HER2 48
Notch EGFR x Notch 46
MAGE-A4 MAGE-A4 x CD3 64
Mesothelin CD16 x mesothelin 47
Muc1 CD16 x MUC1 65