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. 2021 Nov 9;43(1):125–138. doi: 10.1007/s10072-021-05719-9

Table 2.

Summary of primary and secondary outcomes of applied studies

Authors, year Study type N Demographic data Test modality Cognitive/behavioural aspect investigated Task/test I/II level tool
Simeon et al. [26]

Cohort based

Cross-sectional

No control group

1514 HPs

Age: 71.11 ± 4.45

Education: 0–8:47.82%; 8–12: 37.71%; >12: 14.46%

M/F: 0/100%

Telephone Global cognitive efficiency TICS-m I
Motolese et al. [27]

Cohort based

No control group

54 PD patients

Age: 66.5 (range: 59.7–72.2);

Education: Bachelor’s degree: 27.7%; high school: 48.1%; upper secondary school or lower: 22%;

M/F: 67/33%

Telephone Gobal cognitive efficiency NMSQ: GDSsf; PDQ-8; UPDRS-I,-II, and -IV I
Costabile et al. [28]

Cohort based

Control group

497 MS patients;

348 HPs

MS:

Age: 42.4 ± 10.7

Education: 14 ± 3.3

M/F: 29.4/70.6%

HPs:

Age: 40.8 ± 11.9

Education: 16.6 ± 2.8

M/F:24.1/75.9%

Web

Global cognitive efficiency; executive functions;

Mood

Neuro-QoL I
Bacaro et al. [29]

Cohort based

No control group

1989 HPs

Age: 38.4 ± 12.8

M/F: 23.8/76.2%

Web Mood HADS I
Rainero et al. [30]

Cohort based

No control group

4913 caregivers of demented patients (AD, LBD, FTD, VaD)

Patients:

Age: 78.3 ± 8.2

M/F:40.3/ 59,.7%

Telephone

Global cognitive efficiency; executive functions; language; perception;

Attention; memory;

BPSD

CDR;

Ad hoc questionnaire

I
Carlos et al. [31]

Cohort based

No control group

204 CI patients and HPs

Age: ≥65; Mdn

= 82 (75.3–84)

M/F: 42.6/57.4%

Telephone

Mood;

Memory

GDS-5;

Ad hoc questionnaire

I

HPs healthy participants, TICS-m Telephone Interview for Cognitive Status-modified, PD Parkinson’s disease, NMSQ Non-Motor Symptoms Questionnaire, GDSsf Geriatric Depression Scale short form, PDQ-8 Parkinson’s Disease Questionnaire-8 items, UPDRS Unified Parkinson’s Disease Rating Scale, MS multiple sclerosis, Neuro-QoL quality of life in neurological disorders, HADS Hospital Anxiety and Depression Scale, AD Alzheimer’s disease, LBD Lewy body dementia, FTD frontotemporal dementia, VaD vascular dementia, BPSD behavioural and psychological symptoms of dementia, CDR clinical dementia rating, GDS-5 Geriatric Depression Scale-5 items, CI cognitive impairment