Figure 1.

Drug-virus dataset statistics

We used the dataset manually curated by Andersen et al.¹⁷ (Left) Number of drug-virus associations grouped by their known developmental status. The development of broad-spectrum antivirals (BSA) starts with in vitro experiments (e.g., cell culture), moves to animal models, and then to clinical trials in humans (phases I–IV). It terminates with the approval of the drug for commercial use (in red). (Middle) Number of drugs (BSAs) associated to each virus in the dataset. Inset: the word cloud shows the 14 viruses with most associations. The size of the word is proportional to its number of associations and the five most popular viruses among drugs are colored blue. (Right) Number of viruses associated to each drug in the dataset. Inset: the word cloud shows the 18 drugs with most associations and the five most popular drugs among viruses are colored blue.