Figure 7.
Comparison of the enrichment scores for immune cells infiltration and immune-associated functions or pathways between low- and high-risk groups according to the ssGSEA strategy. (A,B) The enrichment scores of 16 immune cells infiltration in the TCGA (A) and ICGC (B) cohorts. (C,D) The enrichment scores of 13 immune-associated functions or pathways in the TCGA (C) and ICGC (D) cohorts. CCR-cytokine-cytokine receptor. *, P<0.05; **, P<0.01; ***, P<0.001. aDCs, activated dendritic cells; APC, antigen-presenting cell; CCR, chemokine-chemokine receptor; DCs, dendritic cells; HLA, human leukocyte antigen; ICGC, International Cancer Genome Consortium; iDCs, inhibited dendritic cells; IFN, interferon; MHC, major histocompatibility complex; pDCs, plasmacytoid dendritic cells; ssGSEA, single-sample gene set enrichment analysis; TCGA, The Cancer Genome Atlas; TIL, tumor infiltrating lymphocytes; Treg, regulatory T cells