Table 2. Top 10 KEGG pathways based on differential peak-associated genes.

No.	Pathway	Peak-related genes with pathway annotation (n, %)	P value	Pathway ID
1	Synthesis and degradation of ketone bodies	1 (1.69)	0.042	ko00072
2	Protein digestion and absorption	4 (6.78)	0.061	ko04974
3	Endocytosis	4 (6.78)	0.061	ko04144
4	Spliceosome	3 (5.08)	0.064	ko03040
5	Terpenoid backbone biosynthesis	1 (1.69)	0.069	ko00900
6	PPAR signaling pathway	2 (3.39)	0.089	ko03320
7	Ribosome	2 (3.39)	0.089	ko03010
8	TGF-beta signaling pathway	2 (3.39)	0.100	ko04350
9	Huntington’s disease	3 (5.08)	0.100	ko05016
10	Circadian rhythm - mammal	1 (1.69)	0.105	ko04710

KEGG, Kyoto Encyclopedia of Genes and Genomes; PPAR, peroxisome proliferator-activated receptors; TGF, transforming growth factor.