Table 1. Patient characteristics.
Characteristic | Data |
---|---|
Age at diagnosis | Median 64 yo (25–84 yo) |
Baseline BMI | Median 26.1 (18.1–46.1) |
Age | |
<50 yo | 7 (7.1%) |
>50 yo | 91 (92.9%) |
Gender | |
Male | 58 (59.2%) |
Female | 40 (40.8%) |
ECOG PS at diagnosis | |
0 | 13 (15.9%) |
1 | 56 (68.3%) |
2–3 | 13 (15.9%) |
Race | |
Caucasian | 73 (74.5%) |
Non-Caucasian | 25 (25.5%) |
Metastatic disease sites | |
Diffuse | 55 (56.1%) |
Single organ | 43 (43.9%) |
1st Line therapy | |
FOLFIRINOX | 34 (34.7%) |
Gemcitabine + nab-paclitaxel | 57 (58.2%) |
Gemcitabine + cisplatin | 2 (2.0%) |
5-FU +/− oxaliplatin | 1 (1.0%) |
Gemcitabine +/− erlotinib | 3 (3.1%) |
Trial | 1 (1.0%) |
CA19-9 at diagnosis | |
<35 | 9 (10.3%) |
<59× ULN | 38 (43.7%) |
>59× ULN | 40 (46.0%) |
Second-line therapy received | |
Yes | 65 (66.3%) |
No | 33 (33.7%) |
CA19-9 at first-line progression | |
<35 | 8 (8.9%) |
<59× ULN | 34 (37.8%) |
>59× ULN | 48 (53.3%) |
Second-line therapy | |
None | 33 (33.7%) |
Gemcitabine + nab-paclitaxel | 31 (31.6%) |
FOLFIRINOX | 8 (8.2%) |
5-FU +/− oxaliplatin | 8 (8.2%) |
5-FU + irinotecan or liposomal irinotecan | 3 (3.1%) |
Gemcitabine based therapy | 12 (12.3%) |
Other | 3 (3.1%) |
Second-line therapy radiographic results | |
Disease-control | 18 (27.7%) |
Progression | 47 (72.3%) |
ECOG, Eastern Cooperative Oncology Group; PS, performance status.