Table 2. Comparison between second-line chemotherapy group and non-second-line chemotherapy group.
Characteristic | Yes | No | P value | |||
---|---|---|---|---|---|---|
N | % | N | % | |||
Age at met diagnosis | <0.001 | |||||
N | 65 | 33 | ||||
Mean (SD) | 61 (10.0) | 68 (10.0) | ||||
Median [Min–Max] | 61 [25–78] | 67 [37–84] | ||||
Baseline BMI or height and weight at baseline | 0.916 | |||||
N | 65 | 33 | ||||
Mean (SD) | 26.88 (4.57) | 27.36 (5.84) | ||||
Median [Min–Max] | 26.10 [18.10–39.10] | 26.90 [20.40–46.10] | ||||
Follow-up (months) | <0.001 | |||||
N | 65 | 33 | ||||
Mean (SD) | 10.11 (6.29) | 4.73 (3.33) | ||||
Median (Min–Max) | 8.51 (3.16–38.05) | 3.88 (1.88–19.29) | ||||
Age | 0.418 | |||||
<50 | 6 | 9.23 | 1 | 3.03 | ||
≥50 | 59 | 90.77 | 32 | 96.97 | ||
Gender | 0.125 | |||||
Male | 42 | 64.62 | 16 | 48.48 | ||
Female | 23 | 35.38 | 17 | 51.52 | ||
ECOG PS at diagnosis | 0.021 | |||||
0 | 10 | 18.87 | 3 | 10.34 | ||
1 | 39 | 73.58 | 17 | 58.62 | ||
2–3 | 4 | 7.55 | 9 | 31.03 | ||
Overweight/obese | 0.588 | |||||
No | 22 | 33.85 | 13 | 39.39 | ||
Yes | 43 | 66.15 | 20 | 60.61 | ||
White | 0.837 | |||||
No | 48 | 73.85 | 25 | 75.76 | ||
Yes | 17 | 26.15 | 8 | 24.24 | ||
Site of disease | 0.437 | |||||
Head | 31 | 47.69 | 19 | 57.58 | ||
Body | 19 | 29.23 | 10 | 30.30 | ||
Tail | 15 | 23.08 | 4 | 12.12 | ||
Metastatic disease sites | 0.524 | |||||
Diffuse | 35 | 53.85 | 20 | 60.61 | ||
Single organ | 30 | 46.15 | 13 | 39.39 | ||
1st line therapy | 0.002 | |||||
FOLFIRINOX | 29 | 44.62 | 5 | 15.15 | ||
GA | 29 | 44.62 | 28 | 84.85 | ||
Gem/Cis | 2 | 3.08 | 0 | 0.00 | ||
FOLFOX/5-FU alone | 1 | 1.54 | 0 | 0.00 | ||
Gem alone or erlotinib combo | 3 | 4.62 | 0 | 0.00 | ||
Trial | 1 | 1.54 | 0 | 0.00 | ||
CA 19-9 at first line start | 0.276 | |||||
<35 | 8 | 14.29 | 1 | 3.23 | ||
<59× ULN | 24 | 42.86 | 14 | 45.16 | ||
>59× ULN | 24 | 42.86 | 16 | 51.61 | ||
CA 19-9 at first line progression | 0.999 | |||||
<35 | 6 | 9.84 | 2 | 6.90 | ||
<59× ULN | 23 | 37.70 | 11 | 37.93 | ||
>59× ULN | 32 | 52.46 | 16 | 55.17 |