Figure 2.

Differentially expressed IRG screening related to immune/stromal scores and enrichment analysis of DEGs. Heatmaps displayed distinct mRNA expression forms between (A) high and low immune score groups and (B) between high and low stromal score groups. (C) Volcano plot of DEGs based on immune score and (D) stromal scores in CC samples. (E) Overlap of stromal score- and immune score-related upregulated DEGs. (F) Overlap of stromal score- and immune score-related downregulated DEGs. (G) The top 8 positions of the GO terminology for biological processes, cellular components, and molecular functions. (H) The top 8 enriched KEGG pathways across the DEGs. IRG, immune-related gene; DEG, differentially expressed gene; CC, colon cancer; GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes.