Table 5. Adverse events comparison of the two groups.

Side reactions	Combination group [chemotherapy group]
	Class 1	Class 2	Class 3	Class 4
Leukopenia	10 [8]	6 [7]	3 [3]	0 [1]
Neutropenia	9 [7]	6 [6]	3 [3]	0 [1]
Neutropenia with fever	0 [0]	0 [0]	1 [0]	0 [1]
Anemia	12 [9]	5 [8]	2 [1]	0 [0]
Thrombocytopenia	8 [6]	5 [6]	0 [0]	0 [0]
Nausea	7 [6]	4 [5]	1 [1]	0 [0]
Vomiting	5 [5]	3 [4]	1 [1]	0 [0]
Fatigue	12 [13]	7 [8]	2 [1]	0 [0]
Elevated transaminase	8 [5]	3 [2]	0 [0]	0 [0]
Hyperbilirubinemia	3 [2]	1 [1]	0 [0]	0 [0]
Hypothyroidism or hyperthyroidism	3 [0]	1 [0]	0 [0]	0 [0]
Rash	3 [0]	2 [0]	0 [0]	0 [0]
Diarrhea	2 [0]	1 [0]	0 [0]	0 [0]
Interstitial pneumonia	0 [0]	1 [0]	0 [0]	0 [0]
Tracheoesophageal fistula	0 [0]	0 [0]	0 [0]	1 [0]
Hemorrhage	0 [0]	0 [0]	0 [0]	0 [1]

The chi-square test or Fisher exact probability method was used.