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. 2021 Oct 26;15:751643. doi: 10.3389/fnins.2021.751643

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Copyright © 2021 Zhou, Du, Liang, Dai, Zhao, Liu, Tan, Mo and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) The network analysis result after removing studies with uncertain serum ferritin level or low serum ferritin level (studies iron supplement for RLS with serum ferritin level upper than 45 ug/l included). (B) The network analysis result of different drugs in treatment of RLS patients with low serum ferritin level. (Gab, Gabapentin; GabE, Gabapentin enacarbil; L-DP, Levodopa; Rot, Rotigotine; Ppx, Pramipexole; Cab, Cabergoline; Rop, Ropinirole; Preg, Pregabalin; Oxy-Na, Oxycodone-naloxone; Pla, Placebo).