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. 2021 Nov 4;14:5801–5816. doi: 10.2147/JIR.S331020

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© 2021 Zhang et al.

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Mice were intratracheally atomized with 5 mg/kg LPS (stimulation for 6, 12, 18, and 24 h) to observe pathological changes. Histological evaluation of lung was conducted by HE staining (A, magnification, × 100; scale bar, 100 μm. Magnification, × 200; scale bar, 50 μm). FITC-albumin permeability was determined by Fluorescence analysis (C, magnification, × 200; scale bar, 50 μm). Inflammatory cytokine of TNF-α (E), IL-1β (F), and IL-6 (G) in the BALF were measured by ELISA kits. (B) Lung injury score of (A). (D) Fluorescence intensity analysis of (C). All data are presented as the mean ± SD of three independent experiments. ^#p < 0.05 vs the control group.