Table 1.
Correlation of HSPA family expression with clinical pathological characteristics in colon cancer analyzed by Logistic regression.
| Characteristics | Total (N) | Odds Ratio (OR) | P value | |
|---|---|---|---|---|
| HSPA1A | Age (>65 vs.<=65) | 478 | 0.901 (0.625-1.298) | 0.576 |
| Gender (Male vs.Female) | 478 | 1.400 (0.977-2.010) | 0.067 | |
| T stage (T3&T4 vs.T1&T2) | 477 | 1.719 (1.090-2.740) | 0.021† | |
| N stage (N1&N2 vs.N0) | 478 | 1.688 (1.170-2.446) | 0.005† | |
| M stage (M1 vs.M0) | 415 | 2.855 (1.634-5.168) | <0.001† | |
| CEA level (>5ng/ml vs.<=5ng/ml) | 303 | 1.870 (1.163-3.027) | 0.01† | |
| HSPA1B | Age (>65 vs.<=65) | 478 | 0.901 (0.625-1.298) | 0.576 |
| Gender (Male vs.Female) | 478 | 1.265 (0.883-1.815) | 0.2 | |
| T stage (T3&T4 vs.T1&T2) | 477 | 1.817 (1.150-2.903) | 0.011† | |
| N stage (N1&N2 vs.N0) | 478 | 1.368 (0.949-1.975) | 0.094 | |
| M stage (M1 vs.M0) | 415 | 1.230 (0.727-2.092) | 0.441 | |
| CEA level (>5 vs.<=5) | 303 | 0.741 (0.459-1.189) | 0.216 | |
| HSPA2 | Age (>65 vs.<=65) | 478 | 0.592 (0.409-0.855) | 0.005† |
| Gender (Male vs.Female) | 478 | 1.223 (0.854-1.754) | 0.272 | |
| T stage (T3&T4 vs.T1&T2) | 477 | 1.311 (0.835-2.071) | 0.241 | |
| N stage (N1&N2 vs.N0) | 478 | 1.190 (0.826-1.716) | 0.352 | |
| M stage (M1 vs.M0) | 415 | 1.313 (0.775-2.243) | 0.313 | |
| CEA level (>5 vs.<=5) | 303 | 1.357 (0.846-2.185) | 0.206 | |
| HSPA4 | Age (>65 vs.<=65) | 478 | 0.933 (0.647-1.344) | 0.709 |
| Gender (Male vs.Female) | 478 | 0.764 (0.533-1.095) | 0.143 | |
| T stage (T3&T4 vs.T1&T2) | 477 | 1.311 (0.835-2.071) | 0.241 | |
| N stage (N1&N2 vs.N0) | 478 | 0.636 (0.439-0.917) | 0.016† | |
| M stage (M1 vs.M0) | 415 | 0.753 (0.441-1.276) | 0.294 | |
| CEA level (>5 vs.<=5) | 303 | 0.631 (0.390-1.013) | 0.058 | |
| HSPA5 | Age (>65 vs.<=65) | 478 | 0.682 (0.472-0.983) | 0.041† |
| Gender (Male vs.Female) | 478 | 0.764 (0.533-1.095) | 0.143 | |
| T stage (T3&T4 vs.T1&T2) | 477 | 1.719 (1.090-2.740) | 0.021† | |
| N stage (N1&N2 vs.N0) | 478 | 1.467 (1.017-2.120) | 0.041† | |
| M stage (M1 vs.M0) | 415 | 0.898 (0.527-1.521) | 0.689 | |
| CEA level (>5 vs.<=5) | 303 | 0.942 (0.588-1.510) | 0.804 | |
| HSPA6 | Age (>65 vs.<=65) | 478 | 1.035 (0.718-1.492) | 0.852 |
| Gender (Male vs.Female) | 478 | 1.000 (0.698-1.432) | 1.000 | |
| T stage (T3&T4 vs.T1&T2) | 477 | 1.817 (1.150-2.903) | 0.011† | |
| N stage (N1&N2 vs.N0) | 478 | 1.467 (1.017-2.120) | 0.041† | |
| M stage (M1 vs.M0) | 415 | 1.556 (0.917-2.676) | 0.104 | |
| CEA level (>5 vs.<=5) | 303 | 1.280 (0.799-2.059) | 0.306 | |
| HSPA7 | Age (>65 vs.<=65) | 478 | 1.035 (0.718-1.492) | 0.852 |
| Gender (Male vs.Female) | 478 | 0.603 (0.419-0.865) | 0.006† | |
| T stage (T3&T4 vs.T1&T2) | 477 | 1.311 (0.835-2.071) | 0.241 | |
| N stage (N1&N2 vs.N0) | 478 | 1.072 (0.744-1.545) | 0.709 | |
| M stage (M1 vs.M0) | 415 | 0.936 (0.551-1.585) | 0.805 | |
| CEA level (>5 vs.<=5) | 303 | 1.091 (0.680-1.753) | 0.718 | |
| HSPA8 | Age (>65 vs.<=65) | 478 | 1.467 (1.017-2.120) | 0.041† |
| Gender (Male vs.Female) | 478 | 0.874 (0.610-1.252) | 0.464 | |
| T stage (T3&T4 vs.T1&T2) | 477 | 0.857 (0.544-1.347) | 0.504 | |
| N stage (N1&N2 vs.N0) | 478 | 0.478 (0.329-0.692) | <0.001† | |
| M stage (M1 vs.M0) | 415 | 0.528 (0.305-0.901) | 0.021† | |
| CEA level (>5 vs.<=5) | 303 | 0.654 (0.405-1.049) | 0.079 | |
| HSPA9 | Age (>65 vs.<=65) | 478 | 0.966 (0.670-1.392) | 0.852 |
| Gender (Male vs.Female) | 478 | 0.790 (0.551-1.132) | 0.200 | |
| T stage (T3&T4 vs.T1&T2) | 477 | 1.179 (0.750-1.857) | 0.476 | |
| N stage (N1&N2 vs.N0) | 478 | 0.757 (0.524-1.091) | 0.136 | |
| M stage (M1 vs.M0) | 415 | 0.665 (0.387-1.129) | 0.134 | |
| CEA level (>5 vs.<=5) | 303 | 0.657 (0.407-1.055) | 0.084 | |
| HSPA12A | Age (>65 vs.<=65) | 478 | 0.812 (0.563-1.170) | 0.264 |
| Gender (Male vs.Female) | 478 | 0.874 (0.610-1.252) | 0.464 | |
| T stage (T3&T4 vs.T1&T2) | 477 | 1.298 (0.826-2.049) | 0.26 | |
| N stage (N1&N2 vs.N0) | 478 | 1.072 (0.744-1.545) | 0.709 | |
| M stage (M1 vs.M0) | 415 | 1.592 (0.938-2.738) | 0.088 | |
| CEA level (>5 vs.<=5) | 303 | 1.530 (0.954-2.468) | 0.079 | |
| HSPA12B | Age (>65 vs.<=65) | 478 | 0.784 (0.543-1.130) | 0.193 |
| Gender (Male vs.Female) | 478 | 0.874 (0.610-1.252) | 0.464 | |
| T stage (T3&T4 vs.T1&T2) | 477 | 1.311 (0.835-2.071) | 0.241 | |
| N stage (N1&N2 vs.N0) | 478 | 1.321 (0.916-1.907) | 0.136 | |
| M stage (M1 vs.M0) | 415 | 0.727 (0.426-1.233) | 0.239 | |
| CEA level (>5 vs.<=5) | 303 | 0.862 (0.537-1.383) | 0.537 | |
| HSPA13 | Age (>65 vs.<=65) | 478 | 0.933 (0.647-1.344) | 0.709 |
| Gender (Male vs.Female) | 478 | 1.309 (0.914-1.877) | 0.143 | |
| T stage (T3&T4 vs.T1&T2) | 477 | 1.243 (0.791-1.960) | 0.346 | |
| N stage (N1&N2 vs.N0) | 478 | 0.966 (0.670-1.392) | 0.852 | |
| M stage (M1 vs.M0) | 415 | 0.628 (0.365-1.066) | 0.088 | |
| CEA level (>5 vs.<=5) | 303 | 1.058 (0.660-1.696) | 0.816 | |
| HSPA14 | Age (>65 vs.<=65) | 478 | 0.812 (0.563-1.170) | 0.264 |
| Gender (Male vs.Female) | 478 | 0.967 (0.675-1.385) | 0.855 | |
| T stage (T3&T4 vs.T1&T2) | 477 | 0.771 (0.488-1.211) | 0.26 | |
| N stage (N1&N2 vs.N0) | 478 | 0.757 (0.524-1.091) | 0.136 | |
| M stage (M1 vs.M0) | 415 | 0.782 (0.459-1.325) | 0.362 | |
| CEA level (>5 vs.<=5) | 303 | 1.080 (0.674-1.731) | 0.75 |
†Bold values represent p < 0.05.