FIGURE 1.

Overview of cerebral autoregulation. General overview of autoregulation and key summary points for this review. A: 2 graphs illustrating the concepts of static and dynamic autoregulation. B: summary of modifiers or factors that have a direct influence on cerebral blood flow (CBF) or on the relationship between blood pressure (BP) and CBF (i.e., autoregulation). Examples include hemodynamics (including the rate of rise or temporal profile of changes in BP) and behavior (sedentary versus exercise). C: summary of the impact of normally functioning autoregulation. D: summary of consequences of impairment in autoregulation in relation to brain health. See text for further details. BBB, blood brain barrier.