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. 2021 Mar 26;101(4):1487–1559. doi: 10.1152/physrev.00022.2020

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FIGURE 8. — Effects of antihypertensive treatment on cerebral blood flow (CBF) in hypertensive patients. Summary of studies that measured effects of antihypertensive treatment on blood pressure (BP) and CBF, using different techniques to measure CBF: transcranial Doppler (TCD; A), MRI arterial spin labeling (B), and Xenon-133 CT (C). A: data from a study investigating antihypertensive treatment in patients with mild or moderate hypertension, after 2–3 wk and after 3 mo of treatment (390). B: summary from 3 studies. Two of these studies (label 1: Ref. 391; label 3: Ref. 392) investigated effects of standard versus intensive BP-lowering treatment. One study (label 2: Ref. 393) investigated effects of stopping antihypertensive treatment (causing BP to increase). C: the study that compared different β-blocking agents to lower BP (394). See text for details on all these studies. CBFV, middle cerebral artery blood velocity.